Poliomyelitis . 93.88

Umar also has polio.

Rap to get for you...

This is the polio virus.

This is a polio vaccine.

With polio it's almost completely different.

Now giving the polio vaccine is simple.

I invented a device called the MarrowMiner, a much less invasive way for harvesting bone marrow.

What the polio eradication program is trying to do is to kill the virus itself that causes polio everywhere on Earth.

We're not trying to control polio.

This virus can only survive in people.

Mice with multiple myeloma, an incurable malignancy of the bone marrow, respond dramatically to the treatment with this drug.

(a) Eliminating poliomyelitis and neonatal tetanus in 1996

His pails are full of milk. The marrow of his bones is moistened.

His pails are full of milk. The marrow of his bones is moistened.

His breasts are full of milk, and his bones are moistened with marrow.

His breasts are full of milk, and his bones are moistened with marrow.

And this is the reason in two countries that hadn't had this disease for more than probably a decade, on opposite sides of the globe, there was suddenly terrible polio outbreaks.

Polio is still a devastating, explosive disease.

The reality of polio today is something very different.

They're going to be the tough ones.

So actually how do we harvest this bone marrow?

The triple vaccination against diphtheria, polio and tetanus (DPT) was introduced in 1961 and the oral polio vaccination in 1962. The

They were terrified of polio, and it would cause public panic.

Twenty years later, they succeeded and developed the polio vaccine.

Finishing polio eradication is the right thing to do.

Polio had also been eradicated in 2002 through immunization campaigns.

Bruce Aylward How we'll stop polio for good

And we found, to our surprise, that we not only got bone marrow out, but we got 10 times the stem cell activity in the marrow from the Marrow Miner, compared to the normal device.

We use those in my field of bone marrow transplantation.

Within a couple of years, every country that started polio eradication rapidly eradicated all three of their polio viruses, with the exception of four countries that you see here.

Now remember, northern India is the perfect storm when it comes to polio.

Finishing polio is a smart thing to do, and it's the right thing to do.

Here's a great idea to spread End polio now.

And Afghanistan, Afghanistan, we think has probably stopped polio repeatedly.

And hand it off to the nurse. She squirts it into a tin.

The second challenge we had was in contrast to the smallpox vaccine, which was very stable, and a single dose protected you for life the polio vaccine is incredibly fragile.

Bruce Aylward Oops. Jon, polio's almost been eradicated.

And at the same time, the polio eradication program has been working to help with a lot of other areas.

And for that reason, polio eradication it's the ultimate in equity and it's the ultimate in social justice.

So, a few years ago, I'm doing my transplant fellowship at Stanford.

And there were more than 10 times as many people living in these countries.

Fake it till you become it. You know? It's not Do it enough until you actually become it and internalize.

Daniel Kraft demos his Marrow Miner a new device that quickly harvests life saving bone marrow with minimal pain to the donor. He emphasizes that the adult stem cells found in bone marrow can be used to treat many terminal conditions, from Parkinson's to heart disease.

And so this informs, among other things, of course, a treatment for bone marrow transplant, which he undertakes.