All this field of view is a single strand of DNA.

The chemical inhibitors used in this treatment target the enzyme polymerase (PARP1), which is normally involved in the repair of DNA single strand breaks a common form of spontaneous DNA lesions. Chemical inhibition of the PARP1 protein results in reduced occurrence of these single strand break repairs.

But in each one of your cells, each strand of DNA is about 30 to 40 million nanometers long.

But to do it, you need a long, single strand of DNA, which is technically very difficult to get.

This is DNA in its classic double helix form.

You'll be familiar with the double helix of DNA.

So if you want to build a human from DNA origami, the problem is, you need a long strand that's 10 trillion trillion bases long.

Double strand again, but inside them, they're infected with a virus that has a nice, long, single stranded genome that we can fold like a piece of paper.

These short DNA sequences are what are going to fold the long strand into this shape that we want to make. So you send an e mail with these sequences in it to a company, and what it does the company pronounces them on a DNA synthesizer.

So DNA's entering the production line from the left hand side, and it hits this collection, these miniature biochemical machines, that are pulling apart the DNA strand and making an exact copy.

So then, we think we can do that. And my first question doing this or one of my questions doing this was how can you make an arbitrary shape or pattern out of DNA? And I decided to use a type of DNA origami, where you take a long strand of DNA and fold it into whatever shape or pattern you might want.

That holds the long strand like this.

And you copy it by going from strand separating.

The damage arising when copying the DNA is repaired with recombination, involving the BRCA1 and BRCA2 proteins. But cells with mutated BRCA1 or BRCA2 genes are unable to undergo recombination and are therefore much more sensitive to an increased level of unrepaired single strand breaks.

The other strand is bundled up into the other sausage.

It was the first DNA phage, DNA virus, DNA genome that was actually sequenced.

Now it wasn't DNA she didn't find DNA.

Each one has a left half that binds the long strand in one place, and a right half that binds it in a different place, and brings the long strand together like this.

When we synthesize it, it comes single stranded, so we can take the blue strand in one tube and make an orange strand in the other tube, and they're floppy when they're single stranded.

And when Watson and Crick in the '50s first decoded this beautiful double helix that we know as the DNA molecule very long, complicated molecule we then started on this journey to understand that inside of that DNA is a language that determines the characteristics, our traits, what we inherit, what diseases we may get.

One set of DNA goes to one side, the other side gets the other set of DNA identical copies of DNA.

So, this is normal DNA, what you think of as normal DNA.

But things aren't so simple for the other strand because it must be copied backwards.

And you can make a map of the Americas and spell DNA with DNA.

It's humanity's DNA.

DNA at 60

So we have discovered that dinosaur DNA, and all DNA, just breaks down too fast.

The next thing is, that virus DNA made stuff that chopped up the bacteria DNA.

Today's dance world is not defined solely by the Royal Winnipeg Ballet or the National Ballet of Canada, but by Liz Lerman's Dance Exchange a multi generational, professional dance company, whose dancers range in age from 18 to 82, and who work with genomic scientists to embody the DNA strand and with nuclear physicists at CERN.

MIT researcher Skylar Tibbits works on self assembly the idea that instead of building something , we can create materials that build themselves, much the way a strand of DNA zips itself together. It's a big concept at early stages Tibbits shows us three in the lab projects that hint at what a self assembling future might look like.

We have our nucleic DNA that everybody thinks of as our DNA, but we also have DNA in our mitochondria, which are the energy packets of the cell.

So, putting together that first strand of capacity becomes critically important, and we must deal with that.

DNA,biology,evolution,science

This is crystallized DNA.

So that's DNA origami. That's one way. There are many ways of casting molecular spells using DNA.

One strand can be copied directly, and you can see these things spooling off to the bottom there.

I extracted DNA from them.

But it's not dinosaur DNA.

Sequin DNA Sequence Submission Tool

And DNA also copies itself.

They're encoded in the DNA.

Paul Rothemund details DNA folding

It feels the DNA origami.

And it has no DNA.

A single strand dipped in water that completely self folds on its own into the letters M I T.