What proteins are involved in signal transduction and also related to pyramidal neurons?

As just a second example these pyramidal cells, large cells, they can span a significant fraction of the brain.

So here's two sort of canonical neurons from a vertebrate and an invertebrate, a human pyramidal neuron from Ramon y Cajal, and another cell to the right, a non spiking interneuron, and this is the work of Alan Watson and Malcolm Burrows many years ago, and Malcolm Burrows came up with a pretty interesting idea based on the fact that this neuron from a locust does not fire action potentials.