The global security architecture is undergoing profound change.

I think that this is a really profound change in the way human affairs are arranged.

Following the Programme's adoption, the bodies responsible for formulating and implementing Mexico's youth policies underwent a profound change.

The Conference provoked a profound change in the population debate by placing priority on issues of human rights.

The change was intended to reflect the profound transformations now under way in Africa as leaders begin to implement NEPAD.

This land in Mexico was in terrible condition, and I've had to mark the hill because the change is so profound.

Further details about the consequences of this profound change in global atmospheric composition and about scientific progress and obstacles in addressing such issues are covered in the section on climate change (see sect. III above).

If SETI does nothing but change the perspective of humans on this planet, then it will be one of the most profound endeavors in history.

Profound leaps forward!

Extremely profound experience.

This can only be achieved through efforts to effect a major change in the lives of older persons so as to turn to take advantage of their profound experience.

I was caught off guard when Stephen Colbert asked me a profound question, a profound question.

That's the profound switch.

And this is extremely profound.

In the least developed countries in Africa and in countries undergoing profound social, economic and political change, volunteering is lower on the agenda of Governments than in other parts of the world.

And that is going to change our worldview in a profound way not in a dissimilar way as 400 years ago, Copernicus' act did, by changing the way we view space and time.

In the face of the profound challenges that confront the world some of long standing, some new our heads of State and Government last week agreed on a far reaching agenda for change.

But it's more profound than fun.

The region needs sustainable policies aimed at bringing about much needed economic diversification. Indeed, without profound structural change, the favorable standard of living that underpins the Gulf states political stability is likely to erode.

There is a profound need to belong.

And finally, there's a profound social impact.

And this seems quite a profound question.

Now, this is a profound biological effect.

That's kind of profound, in a way.

I find it such a profound one.

It requires profound indigenous change that might take the better part of this century to produce. For now, turning the caliphate into yet another failed state in the region seems to be the best possible outcome.

We have to connect with these profound changes.

Swami Dayananda Saraswati The profound journey of compassion

Beauty in the most profound sense of fit.

Profound wisdom but warnings are of no avail.

Profound wisdom but warnings are of no avail.

This sixtieth anniversary year is of profound significance.

I want to talk about how the things we've been taught to think about giving and about charity and about the nonprofit sector are actually undermining the causes we love and our profound yearning to change the world.

The Ministers reiterated their profound condemnation of all acts of terrorism and appreciated the profound role of media in supporting the international efforts to combat terrorism.

A profound statement about the individual and the community.

There's a basic, profound acceleration of this evolutionary process.

And that's a very profound explosion of exponential growth.

But there is something more profound here, something deeper.

Now it's about something else, but it's equally profound.

But there is no denying that technological change nowadays has accelerated, potentially leading to deeper and more profound dislocations. In a much cited 1983 article, the great economist Wassily Leontief worried that the pace of modern technological change is so rapid that many workers, unable to adjust, will simply become obsolete, like horses after the rise of the automobile.

However, this impression correct where the past is concerned might prove deceptive in the future, because two global megatrends will subject the region to more profound change than all the many previous political crises and wars were able to bring about.

The profound convolutions on the surface of a dried cherry.

On November 23, 1654, Pascal had a profound religious experience.

Well, I think it has all sorts of profound implications.

And the social consequences, as we know, are incredibly profound.