There is going to be a big shift towards preventative medicine as we start to be able to identify all of the risk factors that we have as individuals.

The shift system operates in a morning shift from 8.45 to about 13.00, and an afternoon shift until about 18.30.

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This century there's a shift.

These four drivers are fusing together and creating the big shift away from the 20th century, defined by hyper consumption, towards the 21st century, defined by collaborative consumption.

Still a big number, but a big drop.

And we're seeing a shift powered mainly because of information technology a shift in market dominance towards the emerging markets.

I think that's a big, big problem.

And I ask you, please, to go away from here and think about that one radical tactical shift which you could make, which will make that big difference, and then commit a hundred percent to doing it.

She's got a big smile. She's got a big personality.

The most obvious implication is that Francis is weary of polarization, and hopes that the dual canonization will help to propel a shift toward a big tent Catholicism that appeals to a broader range of people. Francis is certainly in a strong position to initiate such a shift his political capital is extraordinarily high, surpassing even that of US President Barack Obama in his early days in office.

I think it was a wonderful paradigm shift.

I invented a plasma antenna, to shift gears.

This is a shift change, one of three.

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One man died after working a 36 hour shift.

So, what's needed is a basic shift in philosophy.

This entails a shift away from earlier events based approaches.

Big skies, big hearts, big, shining continent.

We make a decision it's that big, even though it's not that big.

And it sounds quite simple, but actually it's quite a big, big job.

It's a big community.

It's a big tooth.

Here's a big crowd.

That's a big problem.

That's a big skull.

It's a big skull.

He's a big guy.

It's a big task.

It's a big issue.

He's a big boy.

It's a little big.

So you need a paradigm shift in all of these areas.

Let's shift to a different kind of sea, the cyber sea.

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Now, there was a big effort to solve this problem, and there was actually a big solution.

Big, big problem.

OK, the second big enabler, and this is where I told a big lie.

The next thing that really was a big, big deal was the washing machine.

Still, Africa remains burdened by severe disadvantages, not the least of which is a terrible image. Big corporations don't even have Africa on the map when they consider outsourcing locations, says Sambou Makalou, a native of Mali who tries to persuade US employers to shift service jobs to Africa.

And it has a binary companion that goes around it, so a big star, a big ball of gas.

A big stick, a baton stick.