Antibiotic sensitivity was going down.

This one is an antibiotic.

And your antibiotic goes smaller and clearer.

You've got a lot of pressure favoring antibiotic resistance, so you get increased virulence leading to the evolution of increased antibiotic resistance.

And in Chile, you still had antibiotic sensitivity.

Switch antibiotics so they switched to another antibiotic, Tamiflu.

And once you get increased antibiotic resistance, the antibiotics aren't knocking out the harmful strains anymore.

They got the organism to evolve to mildness, and they got no development of antibiotic resistance.

Some of these infections are actually carrying antibiotic resistance genes now, and that makes them even more difficult.

Did Chile avoid the problem of antibiotic resistance, whereas did Ecuador actually have the beginnings of the problem?

In this case, on the Y axis, we've just got a measure of antibiotic sensitivity and I won't go into that.

But we've got a lot of variation in antibiotic sensitivity in Chile, Peru and Ecuador, and no trend across the years.

The worst possibility is that a very simple germ, like staph, for which we have one antibiotic that still works, mutates.

Naming science as his chief inspiration, Mathieu Lehanneur shows a selection of his ingenious designs an interactive noise neutralizing ball, an antibiotic course in one layered pill, asthma treatment that reminds kids to take it, a living air filter, a living room fish farm and more.

Likewise, if you have the artificial valve option, you're committed to antibiotic therapy whenever you have any intrusive medical treatment at all.

If you could cause an evolutionary decrease in virulence by cleaning up the water supply, you should be able to get an evolutionary decrease in antibiotic resistance.

OK. So, the patient was treated then with a third generation cephalosporin antibiotic and doxycycline, and on day three, it didn't help she had progressed to acute failure.

Of course, of course.

Of course! Of course!

Of course, of course.

Yes, of course. Of course...

Of course, of course. Incognito.

Of course, of course, accommodations.

Well of course, of course.

Yes, of course. Of course.

Yes, of course, of course.

Of course not, of course not.

Of course, it would. Of course.

Of course not. Of course not.

Of course. Of course I do.

Of course. Of course you didn't.

That's Jeffrey, of course. Of course.

But there's another really interesting aspect of this, and this is that if you could control the evolution of virulence, evolution of harmfulness, then you should be able to control antibiotic resistance.

Chosen course is already on course list.

What course shall I set, sir? Course?

But of course. Of course it's necessary.

Yes, of course. Of course. Look at you.

Of course, of course. Back to bed, Barbara.

Of course. Of course. You've been victimised, George.

Of course, of course you can come in.

Of course. To make her jealous, of course.

Course

Of course I can, darling. Of course I can.

Of course you are, sonny. Of course you are.

You understand me, don't you? Of course. Of course.