Chromatic Aberration

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Chromosome one, top left.

I bred that aberration myself.

So this is a single chromosome.

The chromosome is literally blown apart.

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I was the victim of an aberration.

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This huge package of DNA is called a chromosome.

And you have two strands of DNA in each chromosome.

And what's interesting about this experiment is that it's not an aberration.

But what's even more amazing is that if you look at the Y chromosome side, the male side of the story, the Y chromosome Adam only lived around 60,000 years ago.

(Those around him) said By Allah, lo! thou art in thine old aberration.

(Those around him) said By Allah, lo! thou art in thine old aberration.

When the cell feels it's ready to go, it rips apart the chromosome.

But for a son, he can only get the X chromosome from his mother.

It's able to feel when the cell is ready, when the chromosome is correctly positioned.

Carole Lartigue led the effort to actually transplant a bacterial chromosome from one bacteria to another.

And Dan led the team for the synthesis of this over one million base pair chromosome.

Because of the problems with Mycoplasma genitalium and its slow growth about a year and a half ago, we decided to synthesize the much larger chromosome, the mycoides chromosome, knowing that we had the biology worked out on that for transplantation.

This was an African man who gave rise to all the Y chromosome diversity around the world.

It's on the X chromosome. And so in this way you can only get it from your mother.

The Y chromosome, the piece of DNA that makes men men, traces a purely paternal line of descent.

We start with these fragments, and then we have a homologous recombination system that reassembles those into a chromosome.

And what you can do now is, you can outlay exactly what your chromosome is, and what the gene code on that chromosome is right here, and what those genes code for, and what animals they code against, and then you can tie it to the literature.

And the first chromosome we built in 2008 the 500,000 base pair one we simply assigned the names of the authors of the chromosome into the genetic code, but it was using just amino acid single letter translations, which leaves out certain letters of the alphabet.

Such ill treatment is neither routine nor automatic, on the one hand, nor an isolated, occasional aberration, on the other.

Oh, yes. 'Mr. William Cowther, appearing on behalf of the defendant, stated that his client had had a momentary aberration.

And if we isolate just one chromosome, we're going to pull it out and have a look at its structure.

It is a serious aberration in our budgetary arrangements for such a spending limitation to be imposed on the Secretary General.

However, while inter State war has become a relatively rare aberration, threats to human security have by no means been eradicated.

So what we found is if we took the chromosome out of yeast and methylated it, we could then transplant it.

We're here today to announce the first synthetic cell, a cell made by starting with the digital code in the computer, building the chromosome from four bottles of chemicals, assembling that chromosome in yeast, transplanting it into a recipient bacterial cell and transforming that cell into a new bacterial species.

So we took the same mycoides genome that Carole had initially transplanted, and we grew that in yeast as an artificial chromosome.

Women have two copies of that big X chromosome men have the X and, of course, that small copy of the Y.

The use of nuclear energy for military ends can only bring horror and death and is therefore an aberration which, regrettably, mankind devised.

Hence, states the Government, quot in the past, not respecting children apos s rights was an aberration, today it is inadmissible apos quot .

When we did these experiments, though, we could get the chromosome out of yeast but it wouldn't transplant and boot up a cell.

So we're now making several dozen different constructs, because we can vary the cassettes and the genes that go into this artificial chromosome.

There are exciting new forms of gene therapy that overcome the problem of placing the genetic material in the right place on the chromosome.

The war on terror is an aberration. America must defend itself against terrorist attacks, but that cannot be allowed to become the overarching objective of its existence.

When they said Verily Joseph and his brother are dearer to our father than we are, many though we be. Lo! our father is in plain aberration.

When they said Verily Joseph and his brother are dearer to our father than we are, many though we be. Lo! our father is in plain aberration.

Of course, Mr. Ferguson is to be congratulated on having once saved the woman's life, when, in a previous fit of aberration, she threw herself into the Bay.